Recombinant Human Anthrax toxin receptor 2(ANTXR2)

Code CSB-CF001833HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P58335
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence QEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIWECIEKELTA
Source in vitro E.coli expression system
Gene Names ANTXR2
Protein Names Recommended name: Anthrax toxin receptor 2 Alternative name(s): Capillary morphogenesis gene 2 protein Short name= CMG-2
Expression Region 34-489
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Necessary for cellular interactions with laminin and the extracellular matrix.
Involvement in disease Hyaline fibromatosis syndrome (HFS)
Subcellular Location Isoform 1: Cell membrane, Single-pass type I membrane protein, Note=Expressed at the cell surface, SUBCELLULAR LOCATION: Isoform 2: Endoplasmic reticulum membrane, Single-pass type I membrane protein
Protein Families ATR family
Tissue Specificity Expressed in prostate, thymus, ovary, testis, pancreas, colon, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, skeletal muscle, small intestine and spleen.
Database Links

HGNC: 21732

OMIM: 228600

KEGG: hsa:118429

STRING: 9606.ENSP00000306185

UniGene: Hs.162963

Pathway NOD-like receptor signaling pathway

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