Recombinant Human CD27 antigen(CD27)

Code CSB-CF004910HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P26842
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence ATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCHYSCPREEEGSTIPIQEDYRKPEPACSP
Source in vitro E.coli expression system
Gene Names CD27
Protein Names Recommended name: CD27 antigen Alternative name(s): CD27L receptor T-cell activation antigen CD27 T14 Tumor necrosis factor receptor superfamily member 7 CD_antigen= CD27
Expression Region 20-260
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Involvement in disease Lymphoproliferative syndrome 2 (LPFS2)
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Found in most T-lymphocytes.
Database Links

HGNC: 11922

OMIM: 186711

KEGG: hsa:939

STRING: 9606.ENSP00000266557

UniGene: Hs.355307

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