Recombinant Human Killer cell immunoglobulin-like receptor 2DL3(KIR2DL3)

Code CSB-CF012354HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P43628
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names KIR2DL3
Protein Names Recommended name: Killer cell immunoglobulin-like receptor 2DL3 Alternative name(s): CD158 antigen-like family member B2 KIR-023GB Killer inhibitory receptor cl 2-3 MHC class I NK cell receptor NKAT2a NKAT2b Natural killer-associated trans
Expression Region 22-341
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
Subcellular Location Cell membrane, Single-pass type I membrane protein
Protein Families Immunoglobulin superfamily
Database Links

HGNC: 6331

OMIM: 604938

KEGG: hsa:3804

STRING: 9606.ENSP00000342215

UniGene: Hs.654608

Pathway Cellular senescence
Antigen processing and presentation
Natural killer cell mediated cytotoxicity

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