Recombinant Mouse Cyclic AMP-dependent transcription factor ATF-6 beta(Atf6b)

Code CSB-CF002278MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O35451
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Mus musculus (Mouse)
Source in vitro E.coli expression system
Gene Names Atf6b
Protein Names Recommended name: Cyclic AMP-dependent transcription factor ATF-6 beta Short name= cAMP-dependent transcription factor ATF-6 beta Alternative name(s): Activating transcription factor 6 beta Short name= ATF6-beta cAMP response element-binding p
Expression Region 2-699
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE (By similarity).
Subcellular Location Endoplasmic reticulum membrane, Single-pass type II membrane protein, SUBCELLULAR LOCATION: Processed cyclic AMP-dependent transcription factor ATF-6 beta: Nucleus
Protein Families BZIP family, ATF subfamily
Database Links

STRING: 10090.ENSMUSP00000015605

UniGene: Mm.4068

Pathway Estrogen signaling pathway
PI3K-Akt signaling pathway
TNF signaling pathway
Protein processing in endoplasmic reticulum
Th17 cell differentiation
Thyroid hormone synthesis
cGMP-PKG signaling pathway

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