Recombinant Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase(Man1b1)

Code CSB-CF013385MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. A2AJ15
Storage Buffer Tris-based buffer,50% glycerol
Species Mus musculus (Mouse)
Sequence MYPPPAPPPAPHRDFISVTLSLGESYDNSKSRRRRSCWRKWKQLSRLQRNVILFVLGFLILCGFLYSLHTADQWKALSGRPAEVEKMKQEVLPVLPAPQKESAEQEGFADILSQKRQRHFRRGPPHLQIRPPNTVSKDGMQDDAKEREAALGKAQQEENTQRTVISWRGAVIEPEQATELPYKRAEASIKPLVLASKIWKEPAPPNERQKGVIEAFLHAWKGYQKFAWGHDELKPVSKTFSEWFGLGLTLIDALDTMWILGLKQEFKQARKWVSENLDFQKNVDVNLFESTIRILGGLLSTYHLSGDSLFLTKAEDFGKRLMPAFTTPSKIPYSDVNIGTGFAHSPQWTSDSTVAEVTSIQLEFRELSRLTGIKKFQEAVEEVTKHIHSLSGKKDGLVPMFINTNSGLFTHPGVFTLGARADSYYEYLLKQWIQGGKKETQLLEDYVKAIEGIKAHLLRQSQPRKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVHHGLPADHMDLARALMETCYQMNQQMETGLSPEIAHFNMYPRADHKDVEVKPADRHNLLRPETVESLFYLYRVTRDRKYQDWGWEILQSFNKYTRVPSGGYSSINNVQNSHKPEPRDKMESFFVGETLKYLYLLFSDDLELLSLDSCVFNTEAHPLPIWAPA
Source in vitro E.coli expression system
Gene Names Man1b1
Protein Names Recommended name: Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase EC= 3.2.1.113 Alternative name(s): ER alpha-1,2-mannosidase ER mannosidase 1 Short name= ERMan1 Man9GlcNAc2-specific-processing alpha-mannosidase Mannos
Expression Region 1-658
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2) (By similarity).
Subcellular Location Endoplasmic reticulum membrane, Single-pass type II membrane protein
Protein Families Glycosyl hydrolase 47 family
Database Links

KEGG: mmu:227619

STRING: 10090.ENSMUSP00000036996

UniGene: Mm.270798

Pathway Protein processing in endoplasmic reticulum

Related Products

Man1b1 Proteins

Man1b1 Proteins for Mus musculus (Mouse)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 20,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now to get your $50 coupon for protein expression service!

We don't deal in spam.