Recombinant Mouse Zinc transporter 1 (Slc30a1)

Code CSB-CF733704MO
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Source in vitro E.coli expression system
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Product Details

Target Names
Uniprot No.
Alternative Names
Slc30a1; Znt1; Zinc transporter 1; ZnT-1; Solute carrier family 30 member 1
Mus musculus (Mouse)
Expression Region
Target Protein Sequence
Protein Length
full length protein
Tag Info
The following tags are available.
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Please contact us to get it.

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Target Background

May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention.
Gene References into Functions
  1. This study has identified ZnT1 as a novel postsynaptic density protein. PMID: 24602382
  2. C-terminal domain of ZnT-1 was responsible for its protective effect against ischemia-reperfusion , while this part of the ZnT-1 protein did not have a protective effect against the toxicity of zinc PMID: 22193398
  3. Data suggest that expression of zinc homeostatic proteins such as ZnT1 and 3, and metallothioneins 1 and 2, is regulated by crosstalk between synaptic and intracellular pools of Zn(2+). PMID: 20432464
  4. Expression of zinc transporter ZnT1 in mouse choroid epithelial cells suggests that the choroid plexus plays an important role in regulation of zinc homeostasis in the brain. PMID: 15257151
  5. Znt1 provides an essential function during early embryonic development. PMID: 15452870
  6. Cadmium exposure down-regulated ZnT-1 gene expression in the conceptus of mice. PMID: 17669619
  7. The expression of Slc30a1, Slc39a8, and Slc39a10 in the erythrocytes of zinc deficient and replete mice is reported. PMID: 18936201

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
Tissue Specificity
Widely expressed.
Database Links
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