Recombinant Rat Platelet glycoprotein V(Gp5)

Code CSB-CF009688RA
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O08770
Storage Buffer Tris-based buffer,50% glycerol
Species Rattus norvegicus (Rat)
Sequence QPFPCPKTCKCVVRDAVQCSGGSVAHIAELGLPTNLTHILLFRMDRGVLQSHSFSGMTVLQRLMLSDSHISAIDPGTFNDLVKLKTLRLTRNKISHLPRAILDKMVLLEQLFLDHNALRDLDQNLFQKLLNLRDLCLNQNQLSFLPANLFSSLGKLKVLDLSRNNLTHLPQGLLGAQIKLEKLLLYSNRLMSLDSGLLANLGALTELRLERNHLRSIAPGAFDSLGNLSTLTLSGNLLESLPPALFLHVSWLTRLTLFENPLEELPEVLFGEMAGLRELWLNGTHLRTLPAAAFRNLSGLQTLGLTRNPLLSALPPGMFHGLTELRVLAVHTNALEELPEDALRGLGRLRQVSLRHNRLRALPRTLFRNLSSLVTVQLEHNQLKTLPGDVFAALPQLTRVLLGHNPWLCDCGLWPFLQWLRHHLELLGRDEPPQCNGPESRASLTFWELLQGDQWCPSSRGLPPDPPTENALKAPDPTQRPNSSQSWAWVQLVARGESPDNRFYWNLYILLLIAQATIAGFIVFAMIKIGQLFRTLIREELLFEAMGKSSN
Source in vitro E.coli expression system
Gene Names Gp5
Protein Names Recommended name: Platelet glycoprotein V Short name= GPV Alternative name(s): Glycoprotein 5 CD_antigen= CD42d
Expression Region 17-567
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis (By similarity).
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

KEGG: rno:25259

STRING: 10116.ENSRNOP00000047810

UniGene: Rn.138111

Pathway Hematopoietic cell lineage

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