Recombinant Human Tumor necrosis factor receptor superfamily member 12A protein(TNFRSF12A) (Active)

In Stock
Code CSB-AP001931HU
Product Type Tumor Necrosis Factor
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q9NP84
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias Fibroblast growth factor-inducible immediate-early response protein 14, Tweak-receptor, TweakR, CD antigen CD266
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by inhibiting TWEAK- dependent proliferation of human umbilical vein endothelial cells (HUVEC) is less than 30 ng/ml, corresponding to a specific activity of >3.3x104 IU/mg, in the presence of 15 ng/ml of rHuTWEAK.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
Research Area Cancer
Source E.coli
Gene Names TNFRSF12A
Expression Region 28-80aa
Tag Info Tag-Free
Mol. Weight 5.6 kDa
Protein Description Partial
PubMed ID 10751351; 15489334; 11728344; 19241374
Still Have Questions? Leave a Message or Start an on-line Chat
Function Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Database Links

HGNC: 18152

OMIM: 605914

KEGG: hsa:51330

STRING: 9606.ENSP00000326737

UniGene: Hs.355899

Related Products

TNFRSF12A Antibodies

TNFRSF12A Antibodies for Homo sapiens (Human)

TNFRSF12A Proteins

TNFRSF12A Proteins for Homo sapiens (Human)

TNFRSF12A ELISA Kit

TNFRSF12A ELISA Kit for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 20,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now to get your $50 coupon for protein expression service!

We don't deal in spam.