It is difficult for small molecular weight proteins to generate an immune response due to their small molecular weight. Although the fusion of large tags can enhance the immune response, the structure of the target protein will also change, making it difficult to display the correct structure, and most of the immune generated antibodies are also antibodies that recognize tags. CUSABIO has specially built a Nanoparticle technology platform based on HEK293 expression system, which can enhance immune response, display the correct structure, and have complete biological activity.
● Display native conformation with full biological activity
● Can enhance immune response
● Can be used directly for phage screening (provide empty Nanoparticle for reverse screening)
● Can be used for immuno/ELISA/SPR/BLI/cell experiments
Recombinant human full-length CD24 protein
CUSABIO team. Nanoparticle platform. https://www.cusabio.com/c-21090.html