ATL3 Antibody

Code CSB-PA728503LA01HU
Size US$166
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Image
  • Western blot
    All lanes: ATL3 antibody at 2µg/ml
    Lane 1: Jurkat whole cell lysate
    Lane 2: Hela whole cell lysate
    Lane 3: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 61 kDa
    Observed band size: 61 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA728503LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA728503LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ATL3 Polyclonal antibody
Uniprot No.
Target Names
ATL3
Alternative Names
ATL3; Atlastin-3
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Atlastin-3 protein (1-187AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ATL3 Antibody (Product code: CSB-PA728503LA01HU) is Non-conjugated. For ATL3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA728503LB01HU ATL3 Antibody, HRP conjugated ELISA
FITC CSB-PA728503LC01HU ATL3 Antibody, FITC conjugated
Biotin CSB-PA728503LD01HU ATL3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis.
Gene References into Functions
  1. study reports that Sey1/Atl3 and Rtn4 localize to early Legionella-containing vacuoles (LCV) and are critical for pathogen vacuole formation; Sey1/Atl3-dependent ER remodeling contributes to LCV maturation and intracellular replication of L. pneumophila PMID: 28835546
  2. These results suggest that the three ATLs have different capacities to mediate endoplasmic reticulum fusion, with ATL1 being the strongest and ATL3 being the weakest. PMID: 25773277
  3. ATL3 is implicated in the structural organization of intracellular organelles, which may be critical to axonal survival. PMID: 24459106
  4. A family of human GTPases, atlastin-2 and -3 that are closely related to atlastin-1 are described. PMID: 18270207
Involvement in disease
Neuropathy, hereditary sensory, 1F (HSN1F)
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
Tissue Specificity
Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level).
Database Links

HGNC: 24526

OMIM: 609369

KEGG: hsa:25923

STRING: 9606.ENSP00000381844

UniGene: Hs.356719

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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