CCDC106 Antibody

Datasheet

Code	CSB-PA863135LA01HU
Size	US$166
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Image	Western blot All lanes: CCDC106 antibody at 4µg/ml + Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 33 kDa Observed band size: 33 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA863135LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CCDC106 Polyclonal antibody

Uniprot No.

Q9BWC9

Target Names

CCDC106

Alternative Names

CC106_HUMAN antibody; Ccdc106 antibody; Coiled-coil domain-containing protein 106 antibody; HSU79303 antibody; Protein predicted by clone 23882 antibody; ZNF581 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Coiled-coil domain-containing protein 106 protein (1-280AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CCDC106 Antibody (Product code: CSB-PA863135LA01HU) is Non-conjugated. For CCDC106 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA863135LB01HU	CCDC106 Antibody, HRP conjugated	ELISA
FITC	CSB-PA863135LC01HU	CCDC106 Antibody, FITC conjugated
Biotin	CSB-PA863135LD01HU	CCDC106 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Promotes the degradation of p53/TP53 protein and inhibits its transactivity.

Gene References into Functions

Our studies revealed that CCDC106 is associated with non-small cell lung cancer progression and unfavorable prognosis. CCDC106 enhanced Cyclin A2 and Cyclin B1 expression and promoted A549 and H1299 cell proliferation, which depended on AKT signaling. These results suggest that CCDC106 may be a novel target for lung cancer treatment. PMID: 28460455
CCDC106 promotes the degradation of p53 protein and inhibits its transactivity. PMID: 20159018

Subcellular Location

Nucleus. Note=Colocalizes with p53/TP53.

Database Links

HGNC: 30181

OMIM: 613478

KEGG: hsa:29903

UniGene: Hs.82482

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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