CCDC106 Antibody

Code CSB-PA863135LA01HU
Size US$166
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  • Western blot
    All lanes: CCDC106 antibody at 4µg/ml + Mouse brain tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 33 kDa
    Observed band size: 33 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA863135LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CCDC106 Polyclonal antibody
Uniprot No.
Target Names
CCDC106
Alternative Names
CC106_HUMAN antibody; Ccdc106 antibody; Coiled-coil domain-containing protein 106 antibody; HSU79303 antibody; Protein predicted by clone 23882 antibody; ZNF581 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Coiled-coil domain-containing protein 106 protein (1-280AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CCDC106 Antibody (Product code: CSB-PA863135LA01HU) is Non-conjugated. For CCDC106 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA863135LB01HU CCDC106 Antibody, HRP conjugated ELISA
FITC CSB-PA863135LC01HU CCDC106 Antibody, FITC conjugated
Biotin CSB-PA863135LD01HU CCDC106 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Promotes the degradation of p53/TP53 protein and inhibits its transactivity.
Gene References into Functions
  1. Our studies revealed that CCDC106 is associated with non-small cell lung cancer progression and unfavorable prognosis. CCDC106 enhanced Cyclin A2 and Cyclin B1 expression and promoted A549 and H1299 cell proliferation, which depended on AKT signaling. These results suggest that CCDC106 may be a novel target for lung cancer treatment. PMID: 28460455
  2. CCDC106 promotes the degradation of p53 protein and inhibits its transactivity. PMID: 20159018
Subcellular Location
Nucleus. Note=Colocalizes with p53/TP53.
Database Links

HGNC: 30181

OMIM: 613478

KEGG: hsa:29903

UniGene: Hs.82482

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