COPZ1 Antibody

Datasheet

Code	CSB-PA005797LA01HU
Size	US$166
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Image	Western blot All lanes: COPZ1 antibody at 1µg/ml + K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 21, 15, 18, 22, 19 kDa Observed band size: 21 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005797LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA005797LA01HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) COPZ1 Polyclonal antibody

Uniprot No.

P61923

Target Names

COPZ1

Alternative Names

COPZ1 antibody; COPZ antibody; CGI-120 antibody; HSPC181Coatomer subunit zeta-1 antibody; Zeta-1-coat protein antibody; Zeta-1 COP antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Coatomer subunit zeta-1 protein (1-177AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The COPZ1 Antibody (Product code: CSB-PA005797LA01HU) is Non-conjugated. For COPZ1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA005797LB01HU	COPZ1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005797LC01HU	COPZ1 Antibody, FITC conjugated
Biotin	CSB-PA005797LD01HU	COPZ1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

Gene References into Functions

siRNA-mediated COPZ1 depletion causes abortive autophagy, endoplasmic reticulum stress, unfolded protein response and apoptosis in thyroid tumor cells. PMID: 28951131
The knockdown of COPZ1, but not of COPZ2 encoding isoform coatomer protein complex zeta2, caused Golgi apparatus collapse, blocked autophagy, and induced apoptosis in both proliferating and nondividing tumor cells. PMID: 21746916

Subcellular Location

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.

Protein Families

Adaptor complexes small subunit family

Database Links

HGNC: 2243

OMIM: 615472

KEGG: hsa:22818

STRING: 9606.ENSP00000262061

UniGene: Hs.505652

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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