DAP3 Antibody

Code CSB-PA006497ESR2HU
Size US$166
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  • Western blot
    All lanes: 28S ribosomal protein S29, mitochondrial antibody at 10μg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 46, 42 kDa
    Observed band size: 46 kDa

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006497ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DAP3 Polyclonal antibody
Uniprot No.
Target Names
DAP3
Alternative Names
28S ribosomal protein S29 antibody; 28S ribosomal protein S29 mitochondrial antibody; bMRP10 antibody; DAP 3 antibody; DAP-3 antibody; Dap3 antibody; Death associated protein 3 antibody; Death-associated protein 3 antibody; DKFZp686G12159 antibody; FLJ12817 antibody; Ionizing radiation resistance conferring protein antibody; MGC126058 antibody; MGC126059 antibody; Mitochondrial 28S ribosomal protein S29 antibody; mitochondrial antibody; MITOCHONDRIAL RIBOSOMAL PROTEIN S29 antibody; MRP S29 antibody; MRP-S29 antibody; MRPS29 antibody; OTTHUMP00000033480 antibody; OTTHUMP00000033481 antibody; PSD-95/SAP90-binding protein 3 antibody; RT29_HUMAN antibody; S29mt antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 28S ribosomal protein S29, mitochondrial protein (159-398AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in mediating interferon-gamma-induced cell death.
Gene References into Functions
  1. DAP3 plays important roles in mitochondrial function and dynamics PMID: 26306039
  2. DAP3 silencing contributes to breast carcinogenesis. PMID: 25738636
  3. Knockdown of DAP3 expression promoted cell migration. PMID: 24300973
  4. Study demonstrates an inverse association between DAP3 mRNA levels and tumour stage and clinical outcome in breast cancer. PMID: 22287761
  5. identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE); results demonstrated the biological significance of DELE for apoptosis signal mediated by death receptors PMID: 20563667
  6. show that interferon-beta promoter stimulator 1 (IPS-1) binds DAP3 and induces anoikis by caspase activation. PMID: 19644511
  7. Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor PMID: 12099703
  8. not involved in TRAIL-induced apoptosis PMID: 12359235
  9. DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria PMID: 15175341
  10. DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling PMID: 15179560
  11. DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment PMID: 15302871
  12. High DAP3 expression is correlated with thymoma stage PMID: 15679048
  13. study investigated the phosphorylation status of ribosomal DAP3 and mapped the phosphorylation sites by tandem mass spectrometry PMID: 18227431
  14. Complex I and DAP3, hNOA1 may play a role in mitochondrial respiration and apoptosis. PMID: 19103604
  15. DAP3 may participate in mitochondrial maintenance and play a role in the balance between mitochondrial homoeostasis and tumourigenesis in thyroid oncocytic tumors. PMID: 19536094

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Subcellular Location
Mitochondrion.
Protein Families
Mitochondrion-specific ribosomal protein mS29 family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 2673

OMIM: 602074

KEGG: hsa:7818

STRING: 9606.ENSP00000341692

UniGene: Hs.516746

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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