FOXF2 Antibody

1. FOXF2 rs1711972 AA genotype is associated with poor response to therapy in Non-small Cell Lung Cancer. PMID: 28766235
2. miR130a can regulate FOXF2 and function as an oncogene in colorectal cancer. PMID: 28849155
3. FOXF2 deficiency induced mesenchymal-epithelial transition (MET) in Huh7 cell which might facilitate the colonization of circulating tumor cells and the formation of metastasis. PMID: 28582850
4. Cox proportional hazards regression model was used to evaluate the predictive value of FOXF2 mRNA level in non-small cell lung cancer patients PMID: 27487137
5. FOXF2 has a dual role in breast tumorigenesis and functions as either a tumor suppressor or an oncogene depending on the breast tumor subtype. PMID: 27377963
6. MAZ/FOXF2 axis can promote the proliferation of basal like breast cancer cells and suppress disease progression. PMID: 28577976
7. direct targeting of Foxf2 by Shh signaling drives cranial neural crest cell mesenchyme proliferation during upper lip morphogenesis, and disruption of this sequence results in cleft lip. PMID: 28506991
8. Common variants near FOXF2 that are associated with increased stroke susceptibility. PMID: 27068588
9. No correlation was found between FOXF2 promoter methylation and other clinic pathological parameters (age, gender, differentiation, lymph node metastasis, stage, cutting edge, vascular invasion, smoking behavior, and drinking history) in esophageal squamous cell carcinoma. PMID: 28222662
10. Loss of FOXF2 Expression is associated with Hepatocellular Carcinoma. PMID: 25824262
11. results provided statistical evidence of linkage and association between FOXF2 and nonsyndromic cleft lip with or without cleft palate. PMID: 26278207
12. The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. PMID: 25798833
13. MiR-182-induced downregulation of FoxF2. PMID: 25738520
14. Subtype-specific expression and function of FOXF2 in breast cancer cells are regulated through the combined effects of DNA methylation and SP1 transcriptional regulation. PMID: 26070560
15. Foxf2 inactivation in adults resulted in blood-brain barrier breakdown, endothelial thickening, and increased trans-endothelial vesicular transport PMID: 26120030
16. decreased FOXF2 expression indicates the early-onset metastasis and poor prognosis for patients with histological grade II and triple-negative breast cancer. PMID: 23620774
17. MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer. PMID: 23383207
18. 2 unique DNA sequence alterations could have affected FOXF2 on the mRNA or protein level thus contributing to the observed disturbances in genital and palate development PMID: 19276632
19. The distinct expression pattern of FOXF2 in the prostate, its effect on expression of signaling, and its opposing role in the TGFbeta3 pathway, suggests a role for FOXF2 in prostate homeostasis and stroma-epithelial interactions PMID: 19562724

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HGNC: 3810

OMIM: 603250

KEGG: hsa:2295

STRING: 9606.ENSP00000259806

UniGene: Hs.484423