MRPL12 Antibody

Code CSB-PA003285
Size US$100
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  • Western Blot analysis of COLO205 cells using MRP-L12 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
MRPL12
Alternative Names
39S ribosomal protein L12 antibody; 39S ribosomal protein L12, mitochondrial antibody; 5c5-2 antibody; FLJ60124 antibody; L12mt antibody; MGC8610 antibody; mitochondrial antibody; Mitochondrial ribosomal protein L12 antibody; MRP-L12 antibody; MRP-L31/34 antibody; MRPL12 antibody; MRPL7 antibody; MRPL7/L12 antibody; RM12_HUMAN antibody; RPML12 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the Internal region of Human MRP-L12.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
As a component of the mitochondrial large ribosomal subunit, it plays a role in mitochondrial translation. Associates with mitochondrial RNA polymerase to activate transcription.
Gene References into Functions
  1. knock-down of MRPL12 by RNA interference results in instability of POLRMT. PMID: 26586915
  2. This mutation resulted in a decreased steady-state level of MRPL12 protein. PMID: 23603806
  3. the MRPL12 interaction with POLRMT is likely part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation PMID: 17337445
Subcellular Location
Mitochondrion.
Protein Families
Bacterial ribosomal protein bL12 family
Database Links

HGNC: 10378

OMIM: 602375

KEGG: hsa:6182

STRING: 9606.ENSP00000333837

UniGene: Hs.109059

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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