NDUFB10 Antibody

Code CSB-PA003387
Size US$100
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  • Western Blot analysis of HuvEc cells using NDUFB10 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
NDUFB10
Alternative Names
0610011B04Rik antibody; 22kDa antibody; CI PDSW antibody; CI-PDSW antibody; Complex I PDSW antibody; Complex I PDSW subunit antibody; Complex I-PDSW antibody; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 10 22kDa antibody; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 antibody; NADH ubiquinone oxidoreductase PDSW subunit antibody; NADH-ubiquinone oxidoreductase PDSW subunit antibody; NDUBA_HUMAN antibody; NDUFB 10 antibody; Ndufb10 antibody; PDSW antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human NDUFB10.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
Gene References into Functions
  1. findings indicate that mutations in NDUFB10 are a novel cause of complex I deficiency associated with a late stage assembly defect and emphasize the role of intermembrane space proteins for the efficient assembly of complex I. PMID: 28040730
  2. Src kinase inhibition led to a decrease in mitochondrial respiration via a specific decrease in complex I activities which is associated with a lower phosphorylation of the complex I subunit NDUFB10. PMID: 22321370
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
Complex I NDUFB10 subunit family
Database Links

HGNC: 7696

OMIM: 603843

KEGG: hsa:4716

STRING: 9606.ENSP00000268668

UniGene: Hs.513266

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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