PMM1 Antibody

Datasheet

Code	CSB-PA018237LA01HU
Size	US$166
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Image	Western blot All lanes: PMM1 antibody at 2µg/ml Lane 1: HepG2 whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lane 3: 293T whole cell lysate Lane 4: Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA018237LA01HU at dilution of 1:100
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PMM1 Polyclonal antibody

Uniprot No.

Q92871

Target Names

PMM1

Alternative Names

Brain glucose-1,6-bisphosphatase antibody; Phosphomannomutase 1 antibody; PMM 1 antibody; pmm1 antibody; PMM1_HUMAN antibody; PMMH 22 antibody; PMMH-22 antibody; PMMH22 antibody; Sec53 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Phosphomannomutase 1 protein (2-262AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PMM1 Antibody (Product code: CSB-PA018237LA01HU) is Non-conjugated. For PMM1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA018237LB01HU	PMM1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA018237LC01HU	PMM1 Antibody, FITC conjugated
Biotin	CSB-PA018237LD01HU	PMM1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.

Gene References into Functions

a triple mutant of phospomannomutase1 that retains mutase and phosphatase activity, but is unable to bind inosine monophosphate, was characterized. PMID: 29261720
Mutations in phosphomannomutase is associated with ophthalmic manifestations of congenital disorder of glycosylation type 1a PMID: 12789572
human alpha-phosphomannomutase 1 crystallographic structure reveals the structural basis of congenital disorder of glycosylation type 1a PMID: 16540464
analysis of mental development in a patient with phosphomannomutase deficiency who is compound heterozygous for T237R/C241S mutations [case report] PMID: 17186415
The genes GUS and PMM1 are recommended for normalization purposes in gene expression studies of liver tissue from patients with chronic hepatitis. PMID: 18591914
PMM1 is responsible for the degradation of Glc-1,6-P(2) in brain PMID: 18927083

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Subcellular Location

Cytoplasm.

Protein Families

Eukaryotic PMM family

Tissue Specificity

Strong expression in liver, heart, brain, and pancreas; lower expression in skeletal muscle.

Database Links

HGNC: 9114

OMIM: 601786

KEGG: hsa:5372

STRING: 9606.ENSP00000216259

UniGene: Hs.75835

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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