PPP2R3A Antibody

Datasheet

Code	CSB-PA697255
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA697255(PPP2R3A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A172 cells, Primary antibody: CSB-PA697255(PPP2R3A Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q06190

Target Names

PPP2R3A

Alternative Names

AI118493 antibody; DNA for thyroid hormone receptor binding site (258bp) antibody; P2R3A_HUMAN antibody; PP2A subunit B B''-PR72/PR130 antibody; PP2A subunit B B72/B130 isoforms antibody; PP2A subunit B isoform PR72/PR130 antibody; PP2A subunit B isoform R3 isoform antibody; PP2A subunit B isoforms B''-PR72/PR130 antibody; PP2A subunit B isoforms B72/B130 antibody; PP2A subunit B PR72/PR130 isoforms antibody; PP2A subunit B R3 isoform antibody; PPP2R3 antibody; Ppp2r3a antibody; PR130 antibody; PR59 antibody; PR72 antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B'' alpha antibody; Serine/threonine protein phosphatase 2A 72/130 kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human PPP2R3A

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000
IHC	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Gene References into Functions

HDAC1 and HDAC2 suppress the expression of PPP2R3A/PR130, a regulatory subunit of the trimeric serine/threonine phosphatase 2 (PP2A). PMID: 29472538
this study shows the importance of PP2A complexes with the LIM domains of lipoma-preferred partner in cell adhesion and migration dynamics PMID: 26945059
two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A demonstrating the ability or calcium ions to interact with and regulate PP2A PMID: 12524438
The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A. PMID: 17535922
PP2A can be targeted in a calcium-regulated manner to Cdc6 via the PR70 subunit, where it plays a role in regulating protein phosphorylation and stability. PMID: 18397887
PR72 interacts physically and functionally with Naked cuticle. PR72, like Naked cuticle, acts as a negative regulator of the classical Wnt signaling cascade. PMID: 15687260

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Tissue Specificity

Expressed in heart, brain, placenta, lung, muscle and kidney.

Database Links

HGNC: 9307

OMIM: 604944

KEGG: hsa:5523

STRING: 9606.ENSP00000264977

UniGene: Hs.518155

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

PI3K-Akt signaling pathway AMPK signaling Sphingolipid signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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