PRDM12 Antibody

Code CSB-PA140512
Size US$297
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  • Western blot analysis of extracts from HUVEC cells and A549 cells, using PRDM12 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PRDM12 Polyclonal antibody
Uniprot No.
Target Names
PRDM12
Alternative Names
PRDM12 antibody; PFM9PR domain zinc finger protein 12 antibody; EC 2.1.1.- antibody; PR domain-containing protein 12 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human PRDM12.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the positive regulation of histone H3-K9 dimethylation.
Gene References into Functions
  1. The natural history of the PRDM12-CIP disorder. PMID: 26975306
  2. PRDM12 and its functional fly homolog Hamlet are evolutionary conserved master regulators of sensory neuronal specification and play a critical role in pain perception PMID: 25891934
  3. Prdm12 is a key factor in the orchestration of sensory neurogenesis. PMID: 26005867
  4. Down-regulation of PRDM12 is associated with the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion PMID: 14523459
Involvement in disease
Neuropathy, hereditary sensory and autonomic, 8 (HSAN8)
Subcellular Location
Nucleus.
Protein Families
Class V-like SAM-binding methyltransferase superfamily
Tissue Specificity
Not found in adult tissues except in dorsal root ganglia.
Database Links

HGNC: 13997

OMIM: 616458

KEGG: hsa:59335

UniGene: Hs.495311

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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