PSMD5 Antibody

Code CSB-PA018910GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PSMD5
Alternative Names
26S protease subunit S5 basic antibody; 26S proteasome non-ATPase regulatory subunit 5 antibody; 26S proteasome subunit S5B antibody; Protease 26S; subunit 5B antibody; Proteasome (prosome; macropain) 26S subunit; non ATPase; 5 antibody; Proteasome 19S S5B antibody; Proteasome 26S subunit; non ATPase; 5 antibody; PSMD5 antibody; PSMD5_HUMAN antibody; S5B antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PSMD5
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
Gene References into Functions
  1. the critical role of S5b/PSMD5 in negative regulation of proteasome by TNF-alpha/NFkappaB and provide insights into proteasome inhibition in human disease. PMID: 22921402
Protein Families
Proteasome subunit S5B/HSM3 family
Database Links

HGNC: 9563

OMIM: 604452

KEGG: hsa:5711

STRING: 9606.ENSP00000210313

UniGene: Hs.193725

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