RAB20 Antibody

Code CSB-PA003892
Size US$100
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  • Western Blot analysis of A549 cells using Rab 20 Polyclonal Antibody
  • Western Blot analysis of Jurkat K562 NIH-3T3 cells using Rab 20 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
RAB20
Alternative Names
FLJ20429 antibody; RAB20 antibody; RAB20 member RAS oncogene family antibody; RAB20_HUMAN antibody; Ras related protein Rab20 antibody; Ras-related protein Rab-20 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human Rab 20.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Gene References into Functions
  1. Rab20 is specifically and significantly upregulated in the sputum of human patients with active tuberculosis. PMID: 28494243
  2. TdIF1 associates with the RAB20 promoter, and RAB20 gene transcription is reduced in TdIF1-knocked-down cells, suggesting that TdIF1 stimulates RAB20 gene transcription. PMID: 23874396
  3. Regulates connexin 43 intracellular transport. PMID: 18649179
Subcellular Location
Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side.
Protein Families
Small GTPase superfamily, Rab family
Tissue Specificity
Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).
Database Links

HGNC: 18260

KEGG: hsa:55647

STRING: 9606.ENSP00000267328

UniGene: Hs.743563

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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