RASSF4 Antibody

Code CSB-PA003944
Size US$100
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  • Western Blot analysis of HuvEc cells using RASSF4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
RASSF4
Alternative Names
3830411C14Rik antibody; AD037 antibody; AI586137 antibody; MGC105606 antibody; MGC44914 antibody; OTTHUMP00000019493 antibody; Ras association (RalGDS/AF 6) domain family 4 antibody; Ras association (RalGDS/AF 6) domain family member 4 antibody; Ras association domain containing protein 4 antibody; Ras association domain family 4 antibody; Ras association domain-containing protein 4 antibody; RASF4_HUMAN antibody; RASSF 4 antibody; Rassf4 antibody; RP11-285G1.4 antibody; Tumor suppressor RASSF4 antibody
Raised in
Rabbit
Species Reactivity
Human,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human RASSF4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Gene References into Functions
  1. RASSF4 controls store operated calcium entry and endoplasmic reticulum-plasma membrane junctions through ARF6-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiological processes. PMID: 28600435
  2. RASSF4 overexpression inhibits proliferation, invasion, EMT, and Wnt signaling pathway in osteosarcoma cells. PMID: 28081736
  3. the present study suggested that RASSF4 serves as an important tumor suppressor in human nonsmall cell lung cancer . PMID: 26526576
  4. RASSF4 promotes EV71 replication and the production of viral progeny to accelerate the inhibition of the phosphorylation of AKT. PMID: 25701784
  5. expression of SPRR1B is upregulated in oral CSCs/CICs and SPRR1B has a role in cell growth by suppression of RASSF4 PMID: 23954638
  6. Single nucleotide polymorphism in RASSF4 gene is associated with acute lymphoblastic leukemia. PMID: 19066393

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Tissue Specificity
Widely expressed. Frequently down-regulated in tumor cell lines.
Database Links

HGNC: 20793

OMIM: 610559

KEGG: hsa:83937

STRING: 9606.ENSP00000339692

UniGene: Hs.522895

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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