RPAP2 Antibody

Code CSB-PA004025
Size US$100
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  • Western Blot analysis of 293 cells using RPAP2 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
RPAP2
Alternative Names
RPAP2 antibody; C1orf82 antibody; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 antibody; EC 3.1.3.16 antibody; RNA polymerase II-associated protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human RPAP2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.
Gene References into Functions
  1. These results suggest that RPAP2 controls Pol II activity through a direct interaction with Rpb6 PMID: 25639305
  2. During transcription of snRNA genes, Ser7 phosphorylation facilitates recruitment of RPAP2, which in turn both recruits Integrator and dephosphorylates Ser5. PMID: 22137580
Subcellular Location
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner.
Protein Families
RPAP2 family
Database Links

HGNC: 25791

OMIM: 611476

KEGG: hsa:79871

STRING: 9606.ENSP00000359368

UniGene: Hs.444421

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