SPATA16 Antibody

Datasheet

Code	CSB-PA275207
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA275207(SPATA16 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA275207(SPATA16 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 12%SDS-PAGE, Lysate: 50 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA275207(SPATA16 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9BXB7

Target Names

SPATA16

Alternative Names

NYD SP12 antibody; NYD-SP12 antibody; NYDSP12 antibody; SPATA16 antibody; Spermatogenesis associated 16 antibody; Spermatogenesis-associated protein 16 antibody; SPGF6 antibody; SPT16_HUMAN antibody; Testis development protein antibody; Testis development protein NYD-SP12 antibody; Testis specific Golgi protein antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human SPATA16

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000
IHC	1:15-1:50

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion.

Gene References into Functions

This study demonstrates that Spata16 is indispensable for male fertility in mice, as well as in humans. PMID: 29065458
Mutation of SPATA16 is associated with globozoospermia. PMID: 27086357
Case Report: report of a pregnancy obtained in a man with homozygous SPATA16 mutated globozoospermia. PMID: 24825417
results suggest that NYD-SP12 is involved in spermatogenesis, and that NYD-SP12-encoded protein might function in the Golgi apparatus PMID: 12529416
study demonstrated NYD-SP12 protein was involved in the formation of the acrosome during spermatogenesis PMID: 16372119
Results indicate that NYD-SP12 evolves rapidly in both the human and the chimpanzee lineages, which is likely caused by Darwinian positive selection and/or sexual selection. PMID: 17665087
consanguineous family with three affected brothers, in whom we have identified a homozygous mutation in the spermatogenesis-specific gene SPATA16. This is the first example of a nonsyndromic male infertility condition caused by an autosomal gene defect. PMID: 17847006

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Involvement in disease

Spermatogenic failure 6 (SPGF6)

Subcellular Location

Golgi apparatus. Note=Localized to the perinuclear region.

Protein Families

SPATA16 family

Tissue Specificity

Expressed in testis.

Database Links

HGNC: 29935

OMIM: 102530

KEGG: hsa:83893

STRING: 9606.ENSP00000341765

UniGene: Hs.444236

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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