SYNJ2BP Antibody

Code CSB-PA023018GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SYNJ2BP
Alternative Names
SYNJ2BP antibody; OMP25 antibody; Synaptojanin-2-binding protein antibody; Mitochondrial outer membrane protein 25 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SYNJ2BP
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
Gene References into Functions
  1. Data found that SYNJ2BP was decreased in hepatocellular carcinoma (HCC) tissues and cell lines and provide evidence that SYNJ2BP may act as a tumor suppressor during HCC development activating DLL4 pathway. PMID: 27440153
  2. Ubiquilins are a family of chaperones for cytosolically exposed transmembrane domains and use ubiquitin to triage clients, like Omp25, for degradation via coordinated intra- and intermolecular interactions. PMID: 27345149
  3. These results suggest that ARIP2 is a putative growth-promoting factor involved in breast tumorigenesis and tumor development. PMID: 19349195
Subcellular Location
Mitochondrion outer membrane.
Database Links

HGNC: 18955

OMIM: 609411

KEGG: hsa:55333

STRING: 9606.ENSP00000256366

UniGene: Hs.443661

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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