TSGA10 Antibody

Code CSB-PA025126GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TSGA10
Alternative Names
Cancer/testis antigen 79 antibody; CEP4L antibody; CT79 antibody; Predicted testis protein antibody; Testis development protein NYD-SP7 antibody; Testis-specific gene 10 protein antibody; Testis-specific protein 10 antibody; TSG10_HUMAN antibody; Tsga10 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TSGA10
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in spermatogenesis. When overexpressed, prevents nuclear localization of HIF1A.
Gene References into Functions
  1. TSGA10 tends to express variants with shorter 5'UTR. PMID: 28739310
  2. Overexpression of TSGA10 would induce disruption of HIF-1alpha axis and exert potent inhibitory effects on tumor angiogenesis and metastasis. PMID: 26573430
  3. Report role for mir-577/TSGA10 axis in regulation esophageal squamous cell carcinoma progression. PMID: 24294352
  4. TSGA10 should be considered as an autoantigen in a subset of autoimmune polyendocrine syndrome type 1 patients and also in a minority of systemic lupus erythematosus patients PMID: 21198756
  5. TSGA10 could influence the function of antigen presenting cells via its interaction with cytoskeletal proteins such as vimentin PMID: 20797700
  6. over-expressed in 4 of 20 hepatocellular carcinomas (HCC), 1 of 20 colon cancers, 7 of 20 ovarian cancers, 3 of 20 prostate cancers, 1 of 21 malignant melanomas, and 8 of 21 bladder cancers PMID: 15107545
  7. The RT-PCR of TSGA10 expression may help in detection of residual clonal cells leading to early diagnosis and better prognostic qualification of the acute lymphoblastic leukemia. PMID: 16406020
  8. TSGA10 is target of immune reactions in Autoimmune polyendocrine syndrome type 1 (APS1). PMID: 18000009

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Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein Families
CEP135/TSGA10 family
Tissue Specificity
Expressed in the testis, in spermatozoa (at protein level). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach.
Database Links

HGNC: 14927

OMIM: 607166

KEGG: hsa:80705

STRING: 9606.ENSP00000347161

UniGene: Hs.120267

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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