ZFP42 Antibody

Datasheet

Code	CSB-PA856985LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Mouse brain tissue All lanes: ZFP42 antibody at 3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 35 kDa Observed band size: 35 kDa Immunofluorescent analysis of Hela cells using CSB-PA856985LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZFP42 Polyclonal antibody

Uniprot No.

Q96MM3

Target Names

ZFP42

Alternative Names

hREX-1 antibody; Reduced Expression 1 Protein antibody; Reduced expression protein 1 antibody; Rex-1 antibody; REX1 antibody; REX1 transcription factor antibody; Zfp-42 antibody; Zfp42 antibody; ZFP42 zinc finger protein antibody; ZFP42_HUMAN antibody; Zinc finger protein 42 homolog antibody; Zinc finger protein 754 antibody; ZNF754 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Zinc finger protein 42 homolog protein (6-68AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ZFP42 Antibody (Product code: CSB-PA856985LA01HU) is Non-conjugated. For ZFP42 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA856985LB01HU	ZFP42 Antibody, HRP conjugated	ELISA
FITC	CSB-PA856985LC01HU	ZFP42 Antibody, FITC conjugated
Biotin	CSB-PA856985LD01HU	ZFP42 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:2000-1:10000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal.

Gene References into Functions

Results provide evidence that bFGF regulates stemness maintenance in stem cells isolated from human exfoliated deciduous teeth (SHEDs) by enhancing REX-1 mRNA expression via the FGFR and Akt signaling pathways. Moreover, IL-6 is also involved in the bFGF-induced REX1 expression. PMID: 27883224
Results show that a novel pluripotency regulator, REX1, is essential for pluripotency and reprogramming. PMID: 23939908
reduced expression protein-1 (REX-1) is widely expressed in human skin and may be involved in cutaneous differentiation but not in stem cell fate determination. PMID: 21446939
hRex1 binds to the hRex1 promoter region at -298 bp and positively regulates hRex1 transcription, but this regulation is lost in PC-3 human prostate cancer cells. PMID: 20232320
REX1 functions in normal adult epithelial cells and tumorigenic stem cells. PMID: 16865673
Data show that Oct-4, Rex-1, and Gata-4 expression in human mesenchymal stem cells increases cell differentiation efficiency but not hTERT expression. PMID: 17211834
expression of REX-1 in meiotic cells from both testes and ovary indicate a role in meiosis. PMID: 18281244
MAPCs express the OCT4 and REX1 transcription factors, two specific markers of undifferentiated embryonic stem (ES) cells. PMID: 15790780

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Subcellular Location

Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Tissue Specificity

Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem ce

Database Links

HGNC: 30949

OMIM: 614572

KEGG: hsa:132625

STRING: 9606.ENSP00000317686

UniGene: Hs.335787

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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