Recombinant Rat C-X-C motif chemokine 3 protein(Cxcl3) (Active)

In Stock
Code CSB-AP001411RA
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q10746
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias Cytokine-induced neutrophil chemoattractant 2, Macrophage inflammatory protein 2-alpha/beta, MIP2-alpha/beta
Species Rattus norvegicus (Rat)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 5-50 ng/ml.
Purity >96% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSDKSS
Research Area Immunology
Source E.coli
Gene Names Cxcl3
Expression Region 33-101aa
Tag Info Tag-Free
Mol. Weight 7.8 kDa
Protein Description Full Length of Mature Protein
PubMed ID 8043001; 9576061; 8471066; 8607872
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Function Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
Subcellular Location Secreted
Protein Families Intercrine alpha (chemokine CxC) family
Database Links

KEGG: rno:171551

STRING: 10116.ENSRNOP00000038520

UniGene: Rn.10525

Pathway Chemokine signaling pathway
TNF signaling pathway
IL-17 signaling pathway
NOD-like receptor signaling pathway

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