Recombinant Rat Growth-regulated alpha protein(Cxcl1) (Active)

In Stock
Code CSB-AP001391RA
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P14095
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered concentrated solution in 20 mM PB, 150 mM NaCl, pH 7.4 lyophilized
Alias C-X-C motif chemokine 1, CINC-1, Platelet-derived growth factor-inducible protein KC
Species Rattus norvegicus (Rat)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100 ng/ml.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK
Research Area Immunology
Source E.coli
Gene Names Cxcl1
Expression Region 25-96aa
Tag Info Tag-Free
Mol. Weight 7.8 kDa
Protein Description Full Length of Mature Protein
PubMed ID 8482545; 1374243; 2684956; 8607872; 1415488; 7957925; 9192722; 9504410
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Function Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation.
Subcellular Location Secreted
Protein Families Intercrine alpha (chemokine CxC) family
Tissue Specificity At least expressed in the lung and trachea.
Database Links

KEGG: rno:81503

STRING: 10116.ENSRNOP00000003778

UniGene: Rn.10907

Pathway Chemokine signaling pathway
Lipids and Inflammation in Atherogenesis
TNF signaling pathway
IL-17 signaling pathway
NOD-like receptor signaling pathway

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