apex1 Antibody

Code CSB-PA370646XA01DIL
Size Pls inquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) apex1 Polyclonal antibody
Uniprot No. A0MTA1
Target Names apex1
Alternative Names apex1 antibody; apex1a antibody; apex1b antibody; si:ch211-214j24.12 antibody; zgc:66204DNA-(apurinic or apyrimidinic site) lyase antibody; EC 3.1.-.- antibody; EC 4.2.99.18 antibody; APEX nuclease antibody; APEN antibody; Apurinic-apyrimidinic endonuclease 1 antibody; AP endonuclease 1 antibody; zAP1 antibody
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) apex1 protein
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
(From Uniprot)
Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Required for passage through the midblastula transition MBT. May also act as an endoribonuclease involved in the control of single-stranded RNA metabolism. Has no redox activity. Binds DNA and RNA.
Subcellular Location Nucleus. Nucleus, nucleolus. Nucleus speckle. Endoplasmic reticulum. Cytoplasm. Mitochondrion.
Protein Families DNA repair enzymes AP/ExoA family
Database Links

STRING: 7955.ENSDARP00000067373

UniGene: Dr.20170

Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
Join Us with

Subscribe newsletter

Leave a message

© 2007-2022 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1