Abrin-a Antibody

Datasheet

Code	CSB-PA319970ZA01AAC
Size	US$299
Image	Western Blot Positive WB detected in Recombinant protein All lanes: Abrin-a antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 33 kDa Observed band size: 33 kDa
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P11140

Target Names

N/A

Alternative Names

Abrin-a [Cleaved into: Abrin-a A chain (EC 3.2.2.22) (rRNA N-glycosidase); Linker peptide; Abrin-a B chain]

Species Reactivity

Abrus precatorius

Immunogen

Recombinant Abrus precatorius Abrin-a protein (1-251aa )

Immunogen Species

Abrus precatorius (Indian licorice) (Glycine abrus)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Protein G

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The Abrin-a polyclonal antibody can be generated by immunizing a rabbit with the recombinant Abrus precatorius Abrin-a protein (1-251aa). Subsequently, the Abrin-a antibody is obtained from the rabbit serum and purified using protein G. This particular Abrin-a antibody is effective in detecting the Abrin-a protein of Abrus precatorius in ELISA and WB applications.

The main function of Abrin-A, a protein found in the seeds of Abrus precatorius, is to inhibit protein synthesis. Abrin-A acts as a potent toxin that inhibits the activity of ribosomes, the cellular machinery responsible for protein synthesis. This inhibition ultimately leads to cell death.

Customer Reviews and Q&A

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Target Background

Function

The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.

Protein Families

Ribosome-inactivating protein family, Type 2 RIP subfamily

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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