Code | CSB-PA355980ZA01EFA |
Size | US$299 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:2000 |
To produce the BZLF1 polyclonal antibody, a recombinant Epstein-Barr virus BZLF1 protein is utilized as the immunogen. This protein is administered to a rabbit to induce an antibody response. Serum collected from the rabbit contains the resulting polyclonal antibodies. These antibodies are purified through protein G. Its purity is greater than 95%. Stringent validation procedures confirm the antibody's specificity for Epstein-Barr virus BZLF1 protein. The BZLF1 antibody's functional efficacy is further validated in ELISA and WB assays.
The Epstein–Barr virus (EBV) immediate-early transactivator BZLF1 assumes a pivotal role in transitioning EBV infection from its latent state to the lytic or productive phase of EBV's life cycle by triggering a cascade of lytic gene expression. The expression of BZLF1 leads to the transcription of numerous viral genes and replication of the EBV genome, resulting in the generation of progeny viruses and the promotion of B-cell transformation.
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KEGG: vg:3783744