COX16 Antibody

Code CSB-PA885786XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) COX16 Polyclonal antibody
Uniprot No.
Target Names
COX16
Alternative Names
C14orf112 antibody; COX16 antibody; COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) antibody; COX16_HUMAN antibody; Cytochrome c oxidase assembly factor antibody; Cytochrome c oxidase assembly protein COX16 homolog antibody; HSPC203 antibody; mitochondrial antibody; PTD019 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) COX16 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
Gene References into Functions
  1. COX16 is required for assembly of cytochrome C oxidase in human cells and is involved in copper delivery to COX2. PMID: 29355485
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Protein Families
COX16 family
Tissue Specificity
Widely expressed. Expressed at higher level in skeletal muscle, heart and liver.
Database Links

HGNC: 20213

KEGG: hsa:51241

STRING: 9606.ENSP00000374562

UniGene: Hs.709581

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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