Recombinant Human Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16), partial

Code CSB-YP885786HU
MSDS
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Source Yeast
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Code CSB-EP885786HU
MSDS
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Source E.coli
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Code CSB-EP885786HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP885786HU
MSDS
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Source Baculovirus
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Code CSB-MP885786HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
COX16
Uniprot No.
Alternative Names
C14orf112; COX16; COX16 cytochrome c oxidase assembly homolog (S. cerevisiae); COX16_HUMAN; Cytochrome c oxidase assembly factor; Cytochrome c oxidase assembly protein COX16 homolog; HSPC203; mitochondrial; PTD019
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
Gene References into Functions
  1. COX16 is required for assembly of cytochrome C oxidase in human cells and is involved in copper delivery to COX2. PMID: 29355485
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Protein Families
COX16 family
Tissue Specificity
Widely expressed. Expressed at higher level in skeletal muscle, heart and liver.
Database Links

HGNC: 20213

KEGG: hsa:51241

STRING: 9606.ENSP00000374562

UniGene: Hs.709581

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