COX16 Antibody

Code CSB-PA679990
Size US$166
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Image
  • The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA679990(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
  • The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA679990(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
COX16
Alternative Names
C14orf112 antibody; COX16 antibody; COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) antibody; COX16_HUMAN antibody; Cytochrome c oxidase assembly factor antibody; Cytochrome c oxidase assembly protein COX16 homolog antibody; HSPC203 antibody; mitochondrial antibody; PTD019 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human COX16
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:500-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
Gene References into Functions
  1. COX16 is required for assembly of cytochrome C oxidase in human cells and is involved in copper delivery to COX2. PMID: 29355485
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Protein Families
COX16 family
Tissue Specificity
Widely expressed. Expressed at higher level in skeletal muscle, heart and liver.
Database Links

HGNC: 20213

KEGG: hsa:51241

STRING: 9606.ENSP00000374562

UniGene: Hs.709581

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