CTSO Antibody

Code CSB-PA006203ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CTSO Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Cathepsin O antibody; CATO_HUMAN antibody; Ctso antibody; CTSO1 antibody
Raised in
Species Reactivity
Homo sapiens
Recombinant Homo sapiens CTSO protein
Immunogen Species
Homo sapiens (Human)
Purification Method
Protein A/G
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover.
Gene References into Functions
  1. We report that CTSO reduces the protein levels of BRCA1 and ZNF423 through cysteine proteinase-mediated degradation. We also have identified a series of transcription factors of BRCA1 that are regulated by CTSO at the protein level. PMID: 28968398
  2. a single-nucleotide polymorphism near the CTSO gene is a poor prognostic factor in breast cancer although further research might help to reveal the factors linking this genotype and prognosis. PMID: 26482374
Subcellular Location
Protein Families
Peptidase C1 family
Tissue Specificity
Expressed in all tissues examined. High levels seen in the ovary, kidney and placenta while low levels seen in thymus and skeletal muscle.
Database Links

HGNC: 2542

OMIM: 600550

KEGG: hsa:1519

STRING: 9606.ENSP00000414904

UniGene: Hs.75262

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