DKK3 Antibody

Datasheet
Code CSB-PA865568XA01MO

Product Details

Full Product Name Rabbit anti-Mus musculus (Mouse) Dkk3 Polyclonal antibody
Uniprot No. Q9QUN9
Target Names Dkk3
Alternative Names Dickkopf-related protein 3 (Dickkopf-3) (Dkk-3) (mDkk-3) Dkk3
Raised in Rabbit
Species Reactivity Mus musculus (Mouse)
Immunogen Recombinant Mus musculus (Mouse) DKK3 protein
Immunogen Species Mus musculus (Mouse)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Subcellular Location Secreted
Protein Families Dickkopf family
Tissue Specificity Highest expression in brain, eye and heart.
Database Links

KEGG: mmu:50781

STRING: 10090.ENSMUSP00000033036

UniGene: Mm.55143

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