DKK3

DKK3 is a key player that regulates the Wnt/β-catenin signaling pathway, affecting a range of biological processes such as tissue growth, cell death, cell division, metabolism, and immune responses. It's important in several disease fields including heart disease, cancer, immune system disorders, brain diseases, and metabolism, with a special focus on its role in heart and kidney conditions. Evidence shows that DKK3 could be a marker to help diagnose and treat diseases, as it's linked to many health problems. Interestingly, while DKK3 might protect the heart, it could also harm kidney function. Currently, DKK3 is gaining attention as a potential biomarker for cardiovascular and renal health. Its concentrations in biological fluids, including plasma and urine, are closely associated with the onset and progression of these diseases.