Name: GSP1 Antibody
Brand: CUSABIO
SKU: CSB-PA333740ZA01SVG

Product Details

Full Product Name	Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GSP1 Polyclonal antibody
Uniprot No.	P32835
Target Names	GSP1
Alternative Names	GSP1 antibody; CNR1 antibody; CST17 antibody; YLR293C antibody; L8003.19 antibody; GTP-binding nuclear protein GSP1/CNR1 antibody; Chromosome stability protein 17 antibody; GTPase Ran homolog antibody; Genetic suppressor of PRP20-1 antibody
Raised in	Rabbit
Species Reactivity	Saccharomyces cerevisiae
Immunogen	Recombinant Saccharomyces cerevisiae GSP1 protein
Immunogen Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate	Non-conjugated
Clonality	Polyclonal
Isotype	IgG
Purification Method	Protein A/G
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA, WB (ensure identification of antigen)
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables	① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee	① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Lead Time	Made-to-order (12-14 weeks)

Target Background

Function (From Uniprot)	GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Essential for cell viability. By analogy with Ras, Ran may be activated when GTP is exchanged for bound GDP by RCC1 and inactivated when GTP is hydrolyzed by Ran upon activation by RanGAP1.
Gene References into Functions	Cex1p recruits Rna1p from the cytoplasm to the nuclear pore complex and facilitates Rna1p activation of the GTPase activity of Gsp1p by enabling Rna1p to gain access to Gsp1p-GTP bound to the Los1p-tRNA-Gsp1p-GTP export complex. PMID: 22008473 Study proved that the additional beta-wedge in Prp20p is essential for the interaction between Prp20p and Gsp1p. PMID: 21093592 Thus, the Gtr1p-Gtr2p cycle was suggested to regulate the Ran cycle through Yrb2p. PMID: 16143306 Results suggest that the GSP1 pathway could regulate proper telomeric function in yeast through Sir4p. PMID: 16956377
Subcellular Location	Nucleus.
Protein Families	Small GTPase superfamily, Ran family
Database Links	KEGG: sce:YLR293C STRING: 4932.YLR293C

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GSP1 Antibody

Code	CSB-PA333740ZA01SVG
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat