Grem1 Antibody

Datasheet
Code CSB-PA009892ZA01RA

Product Details

Full Product Name Rabbit anti-Rattus norvegicus (Rat) Grem1 Polyclonal antibody
Uniprot No. O35793
Target Names Grem1
Alternative Names Gremlin-1 (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein), Grem1, Cktsf1b1 Drm
Raised in Rabbit
Species Reactivity Rattus norvegicus
Immunogen Recombinant Rat Gremlin-1 (Grem1) (25-184AA)
Immunogen Species Rattus norvegicus (Rat)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order
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Target Data

Function Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis
Subcellular Location Secreted
Protein Families DAN family
Tissue Specificity Highly expressed in the brain, kidney, spleen, and testis and weakly expressed in the lung and liver. Predominantly expressed in differentiated cells as neurons in brain, type I cells in lung and globlet cells in intestine.
Database Links

KEGG: rno:50566

STRING: 10116.ENSRNOP00000035888

UniGene: Rn.42929

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