hmp Antibody

1. comparison of expression of genes involved in folate metabolism and the hmp gene in strains with intact csgD gene and with deletion in csgD; expression of genes for methylene tetrahydrofolate synthesis and formyltetrahydrofolate recycling was higher in cells with CsgD than those without; expression of hmp was lower in the presence of CsgD PMID: 23824318
2. This study demonstrates, for the first time, that Hmp contributes to the protection of uropathogenic Escherichia coli against nitric oxide-mediated toxicity in vitro. PMID: 20399845
3. produces superoxide; during prolonged oxidation of NADH, the spectral signals of Hmp decayed and iron was released in a process prevented by superoxide dismutase or catalase PMID: 15340787
4. The lack of swarming motility of the hmp mutant and its aflagellate state suggest that Hmp synthesis is a metabolic burden in the absence of NO-related stresses. PMID: 17611046
5. HMP catalyzes oxidation of NO to NO(3)(-) (NO-dioxygenase activity) in vivo & in vitro in presence of O(2) & NADH. It also catalyzes reduction of several alkylhydroperoxide substrates into their corresponding alcohols using NADH as electron donor[review] PMID: 18379989

Show More

Hide All

KEGG: ecj:JW2536

STRING: 316385.ECDH10B_2719