IL4R Antibody

Datasheet
Code CSB-PA771258ZA01PI
Uniprot No. Q863Z5
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Pig Interleukin-4 receptor subunit alpha (IL4R), Partial (33-240AA)
Raised in Rabbit
Species Reactivity Sus scrofa
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124), IL4R
Immunogen Species Sus scrofa (Pig)
Gene Names IL4R
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2 (By similarity).
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Type I cytokine receptor family, Type 4 subfamily
Database Links

KEGG: ssc:397614

STRING: 9823.ENSSSCP00000008346

UniGene: Ssc.17244

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Hematopoietic cell lineage
Th1 and Th2 cell differentiation
Th17 cell differentiation

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