Code | CSB-PA325954XA01SZB |
Size | US$299 |
Image | |
The Latest Promotion | |
Have Questions? | Leave a Message or Start an on-line Chat |
To produce the IPAD polyclonal antibody, a recombinant Shigella flexneri IPAD protein (1-332aa) is chosen as the immunogen. This protein is used to immunize a rabbit, resulting in the generation of antibodies. The serum is collected from the rabbit to obtain polyclonal antibodies, which are purified using protein G affinity chromatography. The effectiveness of the IPAD antibody in recognizing Shigella flexneri IPAD protein is confirmed through ELISA and WB assays.
The Shigella flexneri IPAD is a type III secretion system (T3SS) effector protein, which promotes bacterial invasion of host cells. Once inside the host cell, IPAD interacts with other T3SS effectors and components to facilitate the formation of a specialized structure called the "entry complex", allowing Shigella flexneri to penetrate the host cell's membrane and gain entry into the cytoplasm. IPAD plays a crucial role in the early stages of Shigella infection by promoting bacterial invasion and establishing a successful infection.
There are currently no reviews for this product.
KEGG: sfl:CP0126