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| Code | CSB-PA013481ZA01MOW |
| Size | Enquire |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Macaca mulatta (Rhesus macaque) MAPT Polyclonal antibody |
| Uniprot No. | P57786 |
| Target Names | MAPT |
| Alternative Names | MAPT antibody; TAU antibody; Microtubule-associated protein tau antibody; Neurofibrillary tangle protein antibody; Paired helical filament-tau antibody; PHF-tau antibody |
| Raised in | Rabbit |
| Species Reactivity | Macaca mulatta |
| Immunogen | Recombinant Macaca mulatta MAPT protein |
| Immunogen Species | Macaca mulatta (Rhesus macaque) |
| Conjugate | Non-conjugated |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | Protein A/G |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA, WB (ensure identification of antigen) |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
| Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
| Lead Time | Made-to-order (12-14 weeks) |
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| Function (From Uniprot) |
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
| Gene References into Functions |
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| Subcellular Location | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. |
| Tissue Specificity | Expressed in neurons. |
| Database Links |
KEGG: mcc:574327 STRING: 9544.ENSMMUP00000001080 UniGene: Mmu.3731 |
