Cyb5r3 Antibody

Code CSB-PA006320XA01RA
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Rattus norvegicus (Rat) Cyb5r3 Polyclonal antibody
Uniprot No.
Target Names
Cyb5r3
Alternative Names
Cyb5r3 antibody; Dia1 antibody; NADH-cytochrome b5 reductase 3 antibody; B5R antibody; Cytochrome b5 reductase antibody; EC 1.6.2.2 antibody; Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form] antibody
Raised in
Rabbit
Species Reactivity
Rattus norvegicus (Rat)
Immunogen
Recombinant Rattus norvegicus (Rat) Cyb5r3 protein
Immunogen Species
Rattus norvegicus (Rat)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
Gene References into Functions
  1. Results point out the enrichment of cytochrome b 5 reductase isoform 3/cytochrome b 5 system in neuronal cells and structures of the cerebellum and brain stem. PMID: 25850901
  2. The data obtained argue against VDAC1 and in favor of Cyb5R3 involvement in the activation of redox cyclers in the outer mitochondrial membrane. PMID: 24945955
  3. Heterologous expression of an endogenous rat cytochrome b(5)/cytochrome b(5) reductase fusion protein PMID: 11913972
  4. Structure of cytochrome b5 reductase S127P mutant reveals that the adenosine diphosphate (ADP) moiety of the FAD prosthetic group is displaced into the corresponding ADP binding site of the physiologic substrate NADH, thus acting as a substrate inhibitor. PMID: 14609324
Subcellular Location
[Isoform 1]: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side.; [Isoform 3]: Cytoplasm. Note=Produces the soluble form found in erythrocytes.
Protein Families
Flavoprotein pyridine nucleotide cytochrome reductase family
Tissue Specificity
Isoform 1 and isoform 3 are ubiquitously expressed. Isoform 2 is expressed only in erythroid tissues, reticulocytes and liver.
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1