Plaa Antibody

Datasheet
Code CSB-PA018107ZA01MO
Uniprot No. P27612
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Mouse Phospholipase A-2-activating protein (Plaa), partial (495-584AA)
Raised in Rabbit
Species Reactivity Mus musculus
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Phospholipase A-2-activating protein (PLA2P) (PLAP), Plaa, Plap
Immunogen Species Mus musculus (Mouse)
Gene Names Plaa
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (By similarity). Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling
Subcellular Location Nucleus, Cytoplasm, Cell junction, synapse
Protein Families WD repeat PLAP family
Tissue Specificity Expressed in the brain, with highest levels in hippocampal neurons, cerebellar granular cell layer and Purkinje cells (PubMed:28413018).
Database Links

KEGG: mmu:18786

STRING: 10090.ENSMUSP00000102724

UniGene: Mm.490101

Pathway Protein processing in endoplasmic reticulum

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