Stc2 Antibody

Code CSB-PA022822ZA01MO
Size
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Stc2 Polyclonal antibody
Uniprot No.
Target Names
Stc2
Alternative Names
Stanniocalcin-2 (STC-2), Stc2
Raised in
Rabbit
Species Reactivity
Mus musculus
Immunogen
Recombinant Mus musculus Stc2 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
Gene References into Functions
  1. results in MTA2 recruitment to the Stc2 promoter, concomitant with agonist-specific epigenetic modifications targeting histone H4 lysine acetylation PMID: 28696214
  2. STC2 is involved in regulating PAPP-A activity during the development of atherosclerosis PMID: 26983002
  3. Stanniocalcin-2 inhibits proteolytic release of IGF and its ability to cause growth retardation upon transgenic overexpression in mice depends on its proteinase inhibitory function. PMID: 25533459
  4. The Stc2 promoter contains multiple putative xenobiotic response elements. PMID: 23269473
  5. These results suggest that the up-regulation of STC2 gene expression resulting from abnormal alpha-klotho-Fgf23 signaling may contribute to limitation of ectopic calcification. PMID: 22285620
  6. These results define a novel molecular function for STC2 as a negative modulator of Store-Operated Calcium Entry and provide the first direct evidence for the regulation of Ca2+ homeostasis by mammalian STC2. PMID: 21746875
  7. STC2 is linked to PERK signalling in acinar cells and has a role in limiting damage during pancreatic injury. PMID: 21545732
  8. induced STC2 expression is an essential feature of survival component of the unfolded-protein response PMID: 15485913
  9. The murine stanniocalcin 2 gene is a negative regulator of postnatal growth. PMID: 18258678

Show More

Hide All

Subcellular Location
Secreted.
Protein Families
Stanniocalcin family
Tissue Specificity
Found in a variety of tissues including skeletal muscle, small intestine, kidney, liver and brain.
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1