Tg Antibody

Datasheet

Code	CSB-PA023442ZA01RA
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Product Details

Full Product Name

Rabbit anti-Rattus norvegicus (Rat) Tg Polyclonal antibody

Uniprot No.

P06882

Target Names

Alternative Names

TgThyroglobulin antibody; Tg antibody

Raised in

Rabbit

Species Reactivity

Rattus norvegicus

Immunogen

Recombinant Rattus norvegicus Tg protein

Immunogen Species

Rattus norvegicus (Rat)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (12-14 weeks)

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Target Background

Function

Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.

Involvement in disease

Defects in Tg are a cause of a form of hypothyroidism in rdw rat.

Subcellular Location

Secreted.

Protein Families

Type-B carboxylesterase/lipase family

Tissue Specificity

Specifically expressed in the thyroid gland.

Database Links

STRING: 10116.ENSRNOP00000009241

UniGene: Rn.10429

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Related pathways

Th17 cell differentiation Thyroid hormone synthesis

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Tg Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background