Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
| Code | CSB-PA360979ZA01HWY |
| Size | US$299 |
| Image |
|
| The Latest Promotion |  |
| Have Questions? | Leave a Message or Start an on-line Chat |
In the production of the US12 antibody, a rabbit is immunized with recombinant human herpesvirus 1 ICP47 protein (1-88aa), resulting in the production of IgG antibodies by the rabbit's B lymphocytes. The polyclonal US12 antibody is then subjected to meticulous purification through protein G. This US12 antibody can react with human herpesvirus 1 ICP47 protein in ELISA and WB experiments.
The human herpesvirus 1 (HSV-1) US12-encoding protein ICP47 is a polymorphous protein. HSV-1 ICP47 could interfere with RNA splicing in early infection and then shuttle viral mRNA from the nucleus to the cytoplasm in late infection. HSV-1 ICP47's direct interaction with the antigen-dependent transporter (TAP) restricts antigen trafficking, resulting in the generation of empty MHC-I molecules, thus promoting the viral evasion of the immune system.
There are currently no reviews for this product.
KEGG: vg:2703441
