UVSX Antibody

Code CSB-PA361289ZA01EDZ
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Product Details

Full Product Name
Rabbit anti-Enterobacteria phage T4 (Bacteriophage T4) UVSX Polyclonal antibody
Uniprot No.
Target Names
UVSX
Alternative Names
UVSXRecombination and repair protein antibody
Raised in
Rabbit
Species Reactivity
Enterobacteria phage T4
Immunogen
Recombinant Enterobacteria phage T4 UVSX protein
Immunogen Species
Enterobacteria phage T4 (Bacteriophage T4)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.
Gene References into Functions
  1. the uvsX mutant executes recombination-dependent replication but does it by a qualitatively different way. PMID: 22365497
  2. The authors show that the phage helicase UvsW completes the UvsX-promoted strand-exchange reaction, allowing the generation of a simple nicked circular product rather than complex networks of partially exchanged substrates. PMID: 21035462
  3. UvsX suffice to rescue stalled T4 replication forks in vitro PMID: 15194689
  4. allosteric switch residue His195 controls the formation of an asymmetric conformation of UvsX-ssDNA filaments that is active in DNA strand exchange. PMID: 19027026
  5. unlike wild-type UvsX, the ssDNA-dependent ATPase activities of UvsX-H195Q/A are strongly inhibited by both low and high concentrations of UvsY protein. PMID: 19244311

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Protein Families
RecA family
Database Links

KEGG: vg:1258704

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